Table 3 |
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|
The association between dietary factors and lipids with a change in total BML size |
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|
Univariate |
Multivariablea |
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|
|
|
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|
β (95% CI) |
P |
β (95% CI) |
P |
|
|
|
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|
Dietary factors |
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|
Energy intake |
8.60 (-2.46, 19.67) |
0.127 |
15.44 (1.71, 29.16) |
0.028 |
|
Total fat |
1.86 (-9.24, 12.95) |
0.742 |
7.70 (-6.69, 22.09) |
0.293 |
|
Carbohydrate |
14.45 (3.45, 25.46) |
0.010 |
19.27 (6.23, 32.31) |
0.004 |
|
Protein |
5.32 (-5.76, 16.41) |
0.346 |
12.00 (-1.80, 25.79) |
0.088 |
|
Sugars |
14.53 (3.52, 25.53) |
0.010 |
16.90 (4.38, 29.42) |
0.008 |
|
Individual fats |
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|
Monounsaturated fat |
3.37 (-7.73, 14.46) |
0.551 |
10.00 (-4.50, 24.50) |
0.176 |
|
Polyunsaturated fat |
6.26 (-4.83, 17.34) |
0.268 |
11.17 (-1.85, 24.20) |
0.092 |
|
Saturated fat |
-1.88 (-12.97, 9.22) |
0.740 |
1.37 (-12.49, 15.22) |
0.846 |
|
Lipids |
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|
Total cholesterol |
-5.45 (-16.62, 5.72) |
0.338 |
-6.02 (-18.85, 6.82) |
0.357b |
|
Triglycerides |
-7.24 (-18.42, 3.95) |
0.204 |
-6.40 (-19.05, 6.25) |
0.321b |
|
LDL cholesterol |
1.62 (-9.59, 12.83) |
0.776 |
-0.97 (-14.27, 12.32) |
0.885b |
|
HDL cholesterol |
-11.18 (-22.30, -0.05) |
0.049 |
-11.66 (-25.08, 1.76) |
0.088b |
|
|
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|
Values are expressed as a change in total BML size (mm2) per 1 standard deviation increase in dietary or lipid factor. aAdjusted for age, sex, body mass index, baseline BMLs, smoking, cardiovascular disease, diabetes, radiographic osteoarthritis, and time to follow-up. bFurther adjusted for statin use. Boldface denotes statistically significant result. 95% CI, 95% confidence interval; β, beta coefficients; BML, bone marrow lesion; HDL, high-density lipoprotein; LDL, low-density lipoprotein; P, P value. |
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|
Doré et al. Arthritis Research & Therapy 2012 14:R13 doi:10.1186/ar3689 |
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