Defining the cell population responsible for TNFα production. (A) CD64+CD14+ monocytes, (B) CD11c+HLA-DRhi/low myeloid dendritic cells, (C) CD123+ plasmacytoid dendritic cells and (D) CD3+ T lymphocytes from five discoid lupus erythematosus (DLE) and five dermatomyositis (DM) patients, as well as from five controls, were analyzed by flow cytometry to assess their ability to produce intracellular TNFα. Bars show the means and SD. *** P < 0.001 vs controls by Dunnett's multiple comparisons test.
Nabatian et al. Arthritis Research & Therapy 2012 14:R1 doi:10.1186/ar3549