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Highly Accessed Editorial

Autonomic dysfunction in women with fibromyalgia

J Derek Kingsley

Author Affiliations

Indiana State University, Arena C-23, Terre Haute, IN 47809, USA

Arthritis Research & Therapy 2012, 14:103  doi:10.1186/ar3728


See related research by Ribeiro et al., http://arthritis-research.com/content/13/6/R190

Published: 20 February 2012

Abstract

Fibromyalgia (FM) is an idiopathic disease characterized by widespread pain and a myriad of symptoms. Symptoms are diverse and include not only pain but also anxiety, depression, orthostatic intolerance, and cold intolerance. While the etiology of FM is not fully understood, data have suggested that FM may stem from dysfunction of the autonomic nervous system. This dysfunction has been reported at rest, and after a physiological stressor such as exercise. However, few studies have examined the responses during exercise. This novel approach may shed some new light on the effect of exercise in women with FM.