Established rheumatoid arthritis: progression of structural joint damage. Infliximab (IFX) plus methotrexate (MTX) significantly reduces progression of structural joint damage compared with MTX alone, after 1 year of treatment. All patients received concomitant MTX . P < 0.001 for all doses and courses. vdH-S, van der Heijde–Sharp.
Smolen and Emery Arthritis Research & Therapy 2011 13(Suppl 1):S2 doi:10.1186/1478-6354-13-S1-S2