Rapidly progressing disease in rheumatoid arthritis. Matrix risk model for the probability of rapid radiographic progression (RRP) in 1 year, including all selected baseline risk factors, except (a) erythrocyte sedimentation rate (ESR) or (b) C-reactive protein (CRP), generated from the ASPIRE early rheumatoid arthritis dataset. Numbers in each cell represent the percentage (95% confidence interval) of patients who had RRP out of all patients who have the baseline characteristics and receive the initiated treatment as indicated. Predicted probability of RRP: blue, 0 to 9%; green, 10 to 19%; yellow, 20 to 29%; orange, 30 to 39%; red, 40 to 100%. A higher percentage indicates more severe radiographic progression of joint damage. IFX, infliximab; mono, monotherapy; MTX, methotrexate; RF, rheumatoid factor; SJC, swollen joint count. Reprinted with permission from .
Smolen and Emery Arthritis Research & Therapy 2011 13(Suppl 1):S2 doi:10.1186/1478-6354-13-S1-S2