Levels of IL-8, ANGPT-1 and ANGPT-2 in sera from patients with AAV. Levels of IL-8 (A), ANGPT-1 (B) and ANGPT-2 (C) in sera of AAV patients in remission (n = 37) and active disease (n = 18) were measured by ELISA and compared to HC (n = 30). Results are presented as the concentration of each cytokine in serum. Bars denote medians, *, P < 0.05; ***, P < 0.001. AAV, ANCA-associated vasculitides; ANCA, anti-neutrophil cytoplasmic autoantibody; ANGPT, angiopoietin; IL; interleukin.
Hu et al. Arthritis Research & Therapy 2011 13:R201 doi:10.1186/ar3534