Positivity of immunoglobulin G (IgG) and IgM anticitrullinated protein antibodies (ACPAs). The citrullinated epitopes recognized by IgG and IgM ACPAs in each individual. The gray area represents positive reactivity, and the white area represents lack of reactivity. α-eno = α-enolase; CCP = cyclic citrullinated peptide; Fib = fibrinogen; MBP = myelin basic protein; Vim = vimentin.
Suwannalai et al. Arthritis Research & Therapy 2011 13:R195 doi:10.1186/ar3524