Increased FSTL1 expression in the STs from OA patients. (A) FSTL1 mRNA expression in the cryogenic tissue samples from control trauma patients (Con), OA and RA patients, male OA patients and female OA patients. The results are expressed in relative units. The horizontal lines represent the medians. Each point represents an individual value. *, P < 0.05; **, P < 0.01. (B) FSTL1 protein expression in the cryogenic tissue samples from control trauma patients (Con1 to Con7: normal STs from 7 different trauma controls), RA patients (RA1 to RA5: RA STs from 5 different RA patients) and OA patients (OA1 to OA28: OA STs from 28 different OA patients). The male individuals are represented in italics. The FSTL1 immunoreactive band appears as a band with an electrophoretic mobility corresponding to 46 kDa. β-actin was used as a loading control. FSTL1, follistatin-like protein 1; Con, control trauma patients; RA, rheumatoid arthritis; OA, osteoarthritis; ST, synovial tissue.
Wang et al. Arthritis Research & Therapy 2011 13:R193 doi:10.1186/ar3522