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Open Access Research article

Plasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases*

Terrance P O'Hanlon1*, Zhuoyan Li1, Lu Gan1, Mark F Gourley2, Lisa G Rider1 and Frederick W Miller1

Author Affiliations

1 Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, 9000 Rockville Pike, Bethesda, MD 20892 USA

2 National Institute of Arthritis and Musculoskeletal Disease, National Institutes of Health, DHHS, 9000 Rockville Pike, Bethesda, MD 20892 USA

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Arthritis Research & Therapy 2011, 13:R181  doi:10.1186/ar3506

Published: 1 November 2011

Additional files

Additional file 1:

Summary of differential plasma protein levels in comparisons of SAID-affected twins vs. unrelated, matched controls. Excel file documenting all processed, primary data for individual plasma proteins levels in the respective comparison groups as determined by LC-ESI-MS with corresponding statistical analyses (see Materials and methods).

Format: XLS Size: 7.6MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Summary of differential plasma protein levels in comparisons of SAID-affected twins vs. said-unaffected twins. Excel file documenting all processed, primary data for individual plasma proteins levels in the respective comparison groups as determined by LC-ESI-MS with corresponding statistical analyses (see Materials and methods).

Format: XLS Size: 7.9MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Summary of differential plasma protein levels in comparisons of SAID-Unaffected twins vs. unrelated, matched controls. Excel file documenting all processed, primary data for individual plasma proteins levels in the respective comparison groups as determined by LC-ESI-MS with corresponding statistical analyses (see Materials and methods).

Format: XLS Size: 7.6MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data