Axial magnetic resonance imaging scans of a large tophus adjacent to the second metatarsal head of a Pacific islander man with longstanding tophaceous gout. (a) T1-weighted (T1w) image reveals low-signal intensity tophus. (b) T1w post-contrast image reveals rim enhancement and a non-enhancing focus indicating fluid within the tophus (arrow). (c) T2-weighted image shows a crescent of fluid (white) corresponding to the non-enhancing focus on contrast-enhanced images.
McQueen et al. Arthritis Research & Therapy 2011 13:246 doi:10.1186/ar3489