Plots of the two major component loadings from PLS on the whole Leiden Early Arthritis Clinic (n = 704). Each dot indicates one patient. Component scores indicate how strongly each component is represented in each patient. Patients positive for anti-CCP antibodies are blue, whereas negative patients are red. CCP, citrullinated peptide antibody; PLS, partial least squares regression.
De Rooy et al. Arthritis Research & Therapy 2011 13:R180 doi:10.1186/ar3505