Figure 5.

Confocal microscopic analysis of the IL-21-expressing cells in the LSGs of primary SS patients. (a) Immunofluorescent double-staining of IL-21-expressing cells (red) and CXCR5+ cells (blue). (b) Immunofluorescent double-staining of CD4+ T cells (green) and CXCR5+ cells (blue). (c) Immunofluorescent double-staining of IL-21-expressing cells (red) and CD20+ B cells (green). Only the IL-21-expressing cells merged with the CXCR5+ cells. IL-21: Interleukin-21; LSGs: labial salivary glands; SS: Sjögren's syndrome.