Table 3

Coincidence* of autoantibodies in 863 individual systemic sclerosis patients

Antibodies

ACA

ATA

Anti-PM-Scl

Anti-U1-RNP

Anti-RNAP

Anti-fibrilla-rin

Anti-To

Anti-Ku

Anti-Jo-1/Pl-7/OJ

Anti-U11-RNP

Anti-Ro52

Anti-Ro60

Anti-La

AMA

Anti-p25/p23

Anti-NOR-90

Anti-SL

Anti-Sm

Anti-Sp100

Other


ACA

1

0

1

0

0

0

0

0

0

92

11

1

31

28

4

2

0

3

144

ATA

1

2

0

0

0

4

0

0

36

26

6

4

0

1

4

1

0

77

Anti-PM-Scl

0

0

0

0

1

0

0

6

2

0

0

0

0

0

0

0

4

Anti-U1-RNP

1

0

0

0

0

0

11

6

1

2

0

1

0

4

0

11

Anti-RNAP

0

0

0

0

0

5

1

1

1

0

0

1

0

0

5

Anti-fibrillarin

0

0

0

0

0

0

0

1

0

0

0

0

0

8

Anti-To

0

0

0

1

1

0

0

0

0

0

0

0

2

Anti-Ku

0

0

2

2

0

0

0

0

1

0

0

2

Anti-Jo-1/Pl-7/OJ

0

3

0

0

0

0

0

0

0

0

1

Anti-U11-RNP

0

0

0

0

0

0

0

0

0

0

Anti-Ro52

41

15

14

11

2

5

2

2

97

Anti-Ro60

14

6

0

0

0

1

1

33

Anti-La

1

0

0

0

1

0

8

AMA

2

0

1

1

2

29

Anti-p25/p23

1

1

0

1

18

Anti-NOR-90

0

1

0

4

Anti-SL

0

0

3

Anti-Sm

0

0

Anti-Sp100

2

Other

Isolateda

104

153

31

19

23

4

0

4

1

1

2

1

0

0

0

0

1

0

0

79

Totalb

310

260

42

41

33

12

2

10

4

1

187

59

16

41

28

6

9

4

4

363


*Number of patients with co-occurrences of autoantibodies. aIsolated: presence without coincidence of any other autoantibody by all detection methods used. bTotal number of individuals with the respective autoantibody; these numbers mostly are smaller than the sum of all co-occurrences plus the 'isolated' individuals listed because of some triple, quadruple and higher-order coincidences. ACA = anti-centromere antibodies; AMA = antimitochondrial antibodies; ATA = anti-topoisomerase I antibodies;; RNAP = RNA polymerase; RNP = ribonucleoprotein.

Mierau et al. Arthritis Research & Therapy 2011 13:R172   doi:10.1186/ar3495

Open Data