Table 3 |
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|
Coincidence* of autoantibodies in 863 individual systemic sclerosis patients |
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|
Antibodies |
ACA |
ATA |
Anti-PM-Scl |
Anti-U1-RNP |
Anti-RNAP |
Anti-fibrilla-rin |
Anti-To |
Anti-Ku |
Anti-Jo-1/Pl-7/OJ |
Anti-U11-RNP |
Anti-Ro52 |
Anti-Ro60 |
Anti-La |
AMA |
Anti-p25/p23 |
Anti-NOR-90 |
Anti-SL |
Anti-Sm |
Anti-Sp100 |
Other |
|
|
||||||||||||||||||||
|
ACA |
1 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
92 |
11 |
1 |
31 |
28 |
4 |
2 |
0 |
3 |
144 |
|
|
ATA |
1 |
2 |
0 |
0 |
0 |
4 |
0 |
0 |
36 |
26 |
6 |
4 |
0 |
1 |
4 |
1 |
0 |
77 |
||
|
Anti-PM-Scl |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
6 |
2 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
4 |
|||
|
Anti-U1-RNP |
1 |
0 |
0 |
0 |
0 |
0 |
11 |
6 |
1 |
2 |
0 |
1 |
0 |
4 |
0 |
11 |
||||
|
Anti-RNAP |
0 |
0 |
0 |
0 |
0 |
5 |
1 |
1 |
1 |
0 |
0 |
1 |
0 |
0 |
5 |
|||||
|
Anti-fibrillarin |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
8 |
||||||
|
Anti-To |
0 |
0 |
0 |
1 |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
2 |
|||||||
|
Anti-Ku |
0 |
0 |
2 |
2 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
2 |
||||||||
|
Anti-Jo-1/Pl-7/OJ |
0 |
3 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
|||||||||
|
Anti-U11-RNP |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
||||||||||
|
Anti-Ro52 |
41 |
15 |
14 |
11 |
2 |
5 |
2 |
2 |
97 |
|||||||||||
|
Anti-Ro60 |
14 |
6 |
0 |
0 |
0 |
1 |
1 |
33 |
||||||||||||
|
Anti-La |
1 |
0 |
0 |
0 |
1 |
0 |
8 |
|||||||||||||
|
AMA |
2 |
0 |
1 |
1 |
2 |
29 |
||||||||||||||
|
Anti-p25/p23 |
1 |
1 |
0 |
1 |
18 |
|||||||||||||||
|
Anti-NOR-90 |
0 |
1 |
0 |
4 |
||||||||||||||||
|
Anti-SL |
0 |
0 |
3 |
|||||||||||||||||
|
Anti-Sm |
0 |
0 |
||||||||||||||||||
|
Anti-Sp100 |
2 |
|||||||||||||||||||
|
Other |
||||||||||||||||||||
|
Isolateda |
104 |
153 |
31 |
19 |
23 |
4 |
0 |
4 |
1 |
1 |
2 |
1 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
79 |
|
Totalb |
310 |
260 |
42 |
41 |
33 |
12 |
2 |
10 |
4 |
1 |
187 |
59 |
16 |
41 |
28 |
6 |
9 |
4 |
4 |
363 |
|
|
||||||||||||||||||||
|
*Number of patients with co-occurrences of autoantibodies. aIsolated: presence without coincidence of any other autoantibody by all detection methods used. bTotal number of individuals with the respective autoantibody; these numbers mostly are smaller than the sum of all co-occurrences plus the 'isolated' individuals listed because of some triple, quadruple and higher-order coincidences. ACA = anti-centromere antibodies; AMA = antimitochondrial antibodies; ATA = anti-topoisomerase I antibodies;; RNAP = RNA polymerase; RNP = ribonucleoprotein. |
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|
Mierau et al. Arthritis Research & Therapy 2011 13:R172 doi:10.1186/ar3495 |
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