Table 3

Expression of transcription factors in peripheral monocytes

Transcription factor

Normal

pSS


NF-IL6

100.0 ± 16.0

623.6 ± 85.8***

NF-IL6β

100.0 ± 18.5

252.8 ± 51.5*

NF-κB1

100.0 ± 11.4

167.5 ± 23.4*

NF-κB2

100.0 ± 14.9

342.6 ± 45.4***


pSS = primary Sjögren's syndrome. Total RNAs were extracted from monocytes prepared as described in the Table 2 footnote, and the expression levels of NF-IL6, NF-IL6β, NF-κB1 and NF-κB2 were quantitated. The relative expression levels of the genes are indicated. Data represent means ± SEM. Asterisk denotes statistically significant difference between "Normal" and "pSS." *P < 0.05 and ***P < 0.001.

Yoshimoto et al. Arthritis Research & Therapy 2011 13:R170   doi:10.1186/ar3493

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