Table 3 |
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|
Expression of transcription factors in peripheral monocytes |
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|
Transcription factor |
Normal |
pSS |
|
|
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|
NF-IL6 |
100.0 ± 16.0 |
623.6 ± 85.8*** |
|
NF-IL6β |
100.0 ± 18.5 |
252.8 ± 51.5* |
|
NF-κB1 |
100.0 ± 11.4 |
167.5 ± 23.4* |
|
NF-κB2 |
100.0 ± 14.9 |
342.6 ± 45.4*** |
|
|
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|
pSS = primary Sjögren's syndrome. Total RNAs were extracted from monocytes prepared as described in the Table 2 footnote, and the expression levels of NF-IL6, NF-IL6β, NF-κB1 and NF-κB2 were quantitated. The relative expression levels of the genes are indicated. Data represent means ± SEM. Asterisk denotes statistically significant difference between "Normal" and "pSS." *P < 0.05 and ***P < 0.001. |
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Yoshimoto et al. Arthritis Research & Therapy 2011 13:R170 doi:10.1186/ar3493 |
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