Table 2

Expression of BAFF receptors in peripheral monocytes

Receptor

Normal

pSS


TACI

100.0 ± 17.6

121.7 ± 20.4

BAFF-R

100.0 ± 5.9

213.8 ± 14.9***


BAFF = B-cell-activating factor of the TNF family; pSS = primary Sjögren's syndrome; TACI = transmembrane activator and calcium-modulator and cyclophilin ligand interactor. Monocytes (2.5 × 105/ml) prepared from normal individuals ("Normal") and pSS patients ("pSS") were cultured for 96 hours without stimulation. Total RNAs were extracted from the cells, and the expression levels of TACI and BAFF-R were quantitated. The relative expression levels of the genes are indicated. Data represent means ± SEM. Asterisk denotes statistically significant difference between "Normal" and "pSS." ***P < 0.001.

Yoshimoto et al. Arthritis Research & Therapy 2011 13:R170   doi:10.1186/ar3493

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