Table 2

Shared epitope classification according to amino acid sequence at positions 70-74

Allele classification

Amino acid sequence positions 70 to 74

HLA-DRB1 alleles


S1

D-E-RAA

*01:03, *04:02, *11:02-:03, *13:01-:02, *13:04, *13:36, *13:40

Q-A-RAA

*15

S2

Q-K-RAA

*04:01, *04:09, *04:13, *04:35, *04:66

D-K-RAA

*13:03

S3D

D-R-RAA

*11:01, *11:04, *11:27, *12, *13:05-:06, *13:25, *14:22, *16

S3P

Q-R-RAA

*01:01-:02, *04:04-:05, *04:08, *04:10

R-R-RAA

*10:01

X

Q-K-RGR

*03

Q-R-RAE

*04:03, *04:07, *04:11

D-R-RGQ

*07

D-R-RAL

*08

R-R-RAE

*09:01, *14:01, *14:04


HLA = human leucocyte antigen. Data in right column from Gao et al. [6].

Meyer et al. Arthritis Research & Therapy 2011 13:R160   doi:10.1186/ar3479

Open Data