Relative expression of transcription factors BCL6 and ROR-y. The relative mRNA expression of BCL6 and ROR-y in unstimulated, sorted CD4+ T-cells was determined in SLE patients (SLE, n = 7) and healthy controls (HC, n = 4) (A/B). There was no significant difference in the relative expression between these two groups. Bars represent the mean values ± SD. In (C) a representative dot plot of unstimulated and stimulated PBMCs from a SLE patient a healthy control is shown. The percentages of BCL6 and ROR- γt+ CD4+ T-cells in unstimulated (dots) and stimulated samples (squares) are given (D).
Dolff et al. Arthritis Research & Therapy 2011 13:R157 doi:10.1186/ar3474