Expression of IL-21R on B- and T-cells of SLE patients. The histograms show a representative example of the expression of IL-21R on CD19+-cells (A), CD4+-cells (B) and CD8+-cells (C). Positive staining (red line) was compared to an isotype control (grey line). The proportion of receptor positive cells is indicated. D shows the IL-21R expression on CD19+ B-cells and CD4+ and CD8+ T-cells from SLE patients (n = 14) in comparison with healthy controls (HC, n = 6). Horizontal lines represent the mean. P-values were calculated using the nonparametric Mann-Whitney U-test.
Dolff et al. Arthritis Research & Therapy 2011 13:R157 doi:10.1186/ar3474