Table 2

Comparison of the clinical features between RA patients with hRasGRP4 variant 6 and those without

variant 6 (-)

variant 6 (+)

P-value

Age (years)

62.6 ± 6.2

61.4 ± 11.2

0.96*

Male/female

0/10

6/7

0.012^†

DAS28(ESR4)

3.8 ± 1.2

3.4 ± 1.85

0.31*

MMP-3

307 ± 127

148 ± 109

0.057

Disease duration (months)

{mean (range)}

100 (0 to 492)

143 (0 to 504)

0.58*

Patients on therapy

4

8

Patients on no therapy

2

3

0.77^†

The P-values in the first four rows (*) were calculated using Mann-Whitney's U-test; the P-values (^†) were calculated by chi-square test with Yates' correction. DAS28, The Disease Activity Score in 28 joints; MMP, matrix metalloproteinase; RA, rheumatoid arthritis

Hashimoto et al. Arthritis Research & Therapy 2011 13:R154   doi:10.1186/ar3470