Table 2 |
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|
Physical function instruments, metric scores, and sample size requirements |
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|
Standardized response mean |
Cohen's effect size |
Guyatt's effect size |
Minimum detectable difference |
Sample size requirement n (95% CL1) |
|
|
|
|||||
|
Legacy PF-10 |
0.10 |
0.06 |
0.49 |
2.43 |
427 (345, 514) |
|
Legacy HAQ |
0.14 |
0.06 |
0.52 |
1.40 |
143 (113, 176) |
|
Item-Improved PF-10 |
0.09 |
0.05 |
0.59 |
2.16 |
336 (245, 436) |
|
Item-Improved HAQ |
0.13 |
0.05 |
0.73 |
1.14 |
95 (76, 117) |
|
PROMIS PF 10 |
0.13 |
0.05 |
0.52 |
1.47 |
157 (127, 189) |
|
PROMIS PF 20 |
0.13 |
0.05 |
0.63 |
1.24 |
113 (90, 141) |
|
|
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|
1 Confidence Limits HAQ, health assessment questionnaire; Item-Improved, Changes to items intended to improve their performance by altering parameters such as time frame and response options while retaining the same item stem; PF, physical function; PROMIS, Patient-Reported Outcomes Measurement Information System. |
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|
Fries et al. Arthritis Research & Therapy 2011 13:R147 doi:10.1186/ar3461 |
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