Table 4

Rates of myocardial infarction and stroke in the all-control population

All-control population

n = 4,199

Control

n = 1,555

Tocilizumab

4 mg/kg + DMARDs

n = 774

Tocilizumab

8 mg/kg + DMARDs

n = 1,870


Rate/100 PY (95% CI), (number of events)

Myocardial infarction

0.49 (0.13, 1.24), (4)

0.18 (0.00, 0.99), (1)

0.17 (0.02, 0.61), (2)

Stroke

0.24 (0.03, 0.88), (2)

0.0

0.33 (0.09, 0.86), (4)


CI, confidence interval; DMARD, disease-modifying antirheumatic drug; PY, patient-years. Multiple occurrences of the same adverse event in individual patients were counted.

Schiff et al. Arthritis Research & Therapy 2011 13:R141   doi:10.1186/ar3455

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