Table 1

International Society of Nephrology/Renal Pathology Society classification of lupus nephritis

Class I

Minimal mesangial lupus nephritis

Class II

Mesangial proliferative lupus nephritis

Class III

Focal lupus nephritis (<50% glomeruli)

III(A)

Active lesions

III(A/C)

Active and chronic lesions

III(C)

Chronic lesions

Class IV

Diffuse lupus nephritis (>50% glomeruli)

Diffuse segmental (IV-S) or global (IV-G)

IV(A)

Active lesions

IV(A/C)

Active and chronic lesions

IV(C)

Chronic lesions

Class V

Membranous lupus nephritis

Class VI

Advanced sclerosing lupus nephritis

(≥90% globally sclerosed glomeruli without residual activity)


Adapted with premission from Weening et al. [9].

Saxena et al. Arthritis Research & Therapy 2011 13:240   doi:10.1186/ar3378