Use of administrative claims data for comparative effectiveness research of rheumatoid arthritis treatments
1 Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, 1620 Tremont Street, Suite 3030, Boston MA 02120, USA
2 Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, 1620 Tremont Street, Suite 3030, Boston MA 02120, USA
Arthritis Research & Therapy 2011, 13:129 doi:10.1186/ar3472Published: 7 October 2011
Observational studies, particularly those using large administrative claims databases, have become increasingly popular sources of comparative effectiveness or comparative safety research. Studies using claims data often face challenges and criticisms due to the lack of certain clinical information, such as lifestyle risk factors, disease severity, and questionable accuracy of disease diagnoses. A novel, claims-based algorithm to evaluate the clinical effectiveness of rheumatoid arthritis medications has been developed and its performance seems promising, although further validation is needed.