Table 1 |
||||
|
Generalized gait dynamics descriptors for a rat model of lumbar radiculopathy |
||||
|
Body weight |
Pre-operative |
Sham |
NP Alone |
NP + sTNFRII |
|
|
||||
|
Mass (g) |
285 ± 4 |
348 ± 6* |
325 ± 9* |
340 ± 11* |
|
Affected limb |
Pre-operative |
Sham |
NP Alone |
NP + sTNFRII |
|
Max Fz (mN) |
2,156 ± 65 |
2,069 ± 79 |
1,877 ± 88 |
2,016 ± 85 |
|
Iz (mN-s) |
416.6 ± 25.5 |
463.2 ± 31.0 |
325.4 ± 34.5∀,# |
417.9 ± 33.5 |
|
Max F-x (mN) |
-56 ± 15 |
-170 ± 18* |
-111 ± 20 |
-142 ± 20* |
|
I-x (mN-s) |
-3.5 ± 1.6 |
-15.3 ± 2.0* |
-6.7 ± 2.2 |
-10.3 ± 2.1 |
|
t-x (% stance time) |
20.7 ± 2.8 |
30.4 ± 3.4 |
21.2 ± 3.8 |
27.7 ± 3.7 |
|
Max Fx (mN) |
177 ± 18 |
204 ± 22 |
240 ± 25* |
256 ± 24* |
|
Ix (mN-s) |
24.0 ± 3.2 |
28.6 ± 3.9 |
34.0 ± 4.3 |
32.9 ± 4.2 |
|
Max Fy,0-100% (mN) |
280 ± 19 |
301 ± 23 |
301 ± 25 |
286 ± 25 |
|
Max Fy,50-100% (mN) |
182 ± 12 |
203 ± 15 |
185 ± 16 |
176 ± 16 |
|
Iy (mN-sec) |
38.9 ± 2.2 |
46.2 ± 4.3 |
38.0 ± 4.2 |
40.4 ± 2.8 |
|
Contralateral limb |
Pre-operative |
Sham |
NP Alone |
NP + sTNFRII |
|
Max Fz (mN) |
2,154 ± 74 |
2,079 ± 83 |
1,984 ± 97 |
1,914 ± 81 |
|
Iz (mN-s) |
439.5 ± 29.0 |
475.6 ± 32.6 |
488.3 ± 38.0 |
440.3 ± 31.8 |
|
Max F-x (mN) |
-79 ± 17 |
-160 ± 19* |
-124 ± 22 |
-116 ± 19 |
|
I-x (mN-s) |
-5.7 ± 1.9 |
-13.3 ± 2.1* |
-11.6 ± 2.4 |
-6.7 ± 2.0 |
|
t-x (% stance time) |
23.4 ± 3.2 |
30.4 ± 3.6 |
22.7 ± 4.2 |
18.1 ± 3.5 |
|
Max Fx (mN) |
169 ± 21 |
263 ± 23* |
274 ± 27* |
304 ± 23* |
|
Ix (mN-s) |
23.0 ± 3.6 |
33.2 ± 4.1 |
40.2 ± 4.7* |
42.4 ± 3.9* |
|
Max Fy,0-100% (mN) |
285 ± 21 |
304 ± 24 |
276 ± 28 |
231 ± 23 |
|
Max Fy,50-100% (mN) |
167 ± 14 |
210 ± 16 |
182 ± 18 |
184 ± 15 |
|
Iy (mN-sec) |
40.5 ± 2.6 |
45.2 ± 4.3 |
49.1 ± 5.7 |
36.2 ± 3.6 |
|
|
||||
|
∀, P <0.05 vs. contralateral control limb *, P <0.05 vs. pre-operative control #, P <0.05 vs. sham control Data presented as mean ± standard error |
||||
|
Allen et al. Arthritis Research & Therapy 2011 13:R137 doi:10.1186/ar3451 |
||||
