Stride length and step widths in rats with lumbar radiculopathy (five days post-operation). A significant correlation between stride length and velocity is observed in walking rats (upper left); raw data with a linear fit of the pre-operative data are shown. As velocity increases, stride length increases. Even after accounting for this correlation, stride lengths were found to increase in sham controls, animals with NP alone, and animals with NP and sTNFRII (*, lower left, P <0.016). A weaker, but important, correlation is also seen between step width and velocity (upper right); again, raw data with a linear fit of the pre-operative are shown. Here, as velocity increases, step widths narrow; however, after accounting for this correlation, no differences were observed in step width between groups (lower right). Data in lower graphs are presented as mean ± standard error.
Allen et al. Arthritis Research & Therapy 2011 13:R137 doi:10.1186/ar3451