Unbalanced, asymmetric gait in rats with lumbar radiculopathy (five days post-operation). Unbalanced, asymmetric gaits were observed in animals with NP alone (∀, P <0.032), while all other groups did not differ significantly from the mathematical definition of balanced, symmetric gait. The percentage stance time imbalance observed in animals with NP alone differed from both preoperative (*, P = 0.025) and sham controls (#, P = 0.013), and this imbalance was improved in animals receiving NP and sTNFRII relative to animals with NP alone (^, P = 0.012). Gait symmetry of animals with NP alone was also significantly different from pre-operative controls (*, P = 0.009). Data are presented as mean ± standard error.
Allen et al. Arthritis Research & Therapy 2011 13:R137 doi:10.1186/ar3451