Table 3

Distribution of ACP1 alleles in RA patients with and without CV events

Haploype, no. (frequency)

ACP1 allele

Haplotype

RA with CV

RA without CV

P-adj*

OR*


ACP1*A

CG

110 (0.276)

525 (0.281)

0.217

0.76

ACP1*B

CA

270 (0.678)

1,263 (0.676)

0.859

1.04

ACP1*C

TA

18 (0.045)

80 (0.043)

0.024

2.43


CV, cardiovascular; RA, rheumatoid arthritis The order of the SNPs is rs11553742|rs7576247.

* multiple regression adjusted by age at diagnosis of the disease, gender, shared epitope status, hypertension, diabetes mellitus, dyslipidemia, obesity and smoking habit.

Teruel et al. Arthritis Research & Therapy 2011 13:R116   doi:10.1186/ar3401

Open Data