Open Access Research article

Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients

María Teruel1*, Jose-Ezequiel Martin1, Carlos González-Juanatey2, Raquel López-Mejias3, Jose A Miranda-Filloy4, Ricardo Blanco3, Alejandro Balsa5, Dora Pascual-Salcedo5, Luis Rodriguez-Rodriguez6, Benjamin Fernández-Gutierrez6, Ana M Ortiz7, Isidoro González-Alvaro7, Carmen Gómez-Vaquero8, Nunzio Bottini9, Javier Llorca10, Miguel A González-Gay3 and Javier Martin1

Author Affiliations

1 Instituto de Parasitología y Biomedicina "López-Neyra", IPBLN-CSIC, Avd. del Conocimiento s/n. 18010. Granada, Spain

2 Division of Cardiology, Hospital Xeral-Calde, Dr Ochoa s/n, 27004, Lugo, Spain

3 Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IFIMAV, Avenida de Valdecilla s/n, 39008, Santander, Spain

4 Rheumatology Division, Hospital Xeral-Calde, Dr Ochoa s/n, 27004, Lugo, Spain

5 Rheumatology Service, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046, Madrid, Spain

6 Servicio de Reumatología, Hospital Clinico San Carlos, C/Profesor Martín Lagos, S/N, 28040 Madrid, Spain

7 Rheumatology Service, Hospital Universitario La Princesa, C/Diego de León, 62,28006, Madrid, Spain

8 Rheumatology Service, Hospital Universitari Bellvitge, Feixa Llarga s/n, 08907, Hospitalet de Llobregat, Barcelona, Spain

9 Division of Cell Biology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA

10 Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IFIMAV, Avenida del Cardenal Herrera Oria, 39011, Santander, Spain

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Arthritis Research & Therapy 2011, 13:R116  doi:10.1186/ar3401

Published: 18 July 2011

Additional files

Additional file 1:

Genotype and allele distribution of ACP1 polymorphisms in Spanish RA patients and healthy subjects. Supplementary table S1 shows the genotype and allele frequencies of ACP1 polymorphisms in Spanish RA patients and healthy controls. That table also shows the lack of association among cases and controls.

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Additional file 2:

Distribution of ACP1 alleles in Spanish RA patients and healthy controls. Supplementary table S2 shows the frequencies of ACP1 alleles in Spanish RA patients and individuals controls. No association was observed.

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