Table 2

Low incidence of disease when arthritic IIJ mice were crossed with four other inbred strainsa

Crossb

Cage

F1

F2


AR × BALB/c

1

0 of 13

2 of 25

2

0 of 18

0 of 19

AR × FVB

1

0 of 13

0 of 23

2

1 of 22

2 of 38

AR × DBA1

1

0 of 20

0 of 21

2

0 of 13

1 of 20

AR × C3H

1

1 of 16

0 of 24

2

0 of 15

0 of 25


aMice were followed for an average of 120 postnatal days and a minimum of 90 postnatal days, except in rare cases (< 2.5%) when males were killed earlier because of fighting with cagemates. bArthritic (AR) males from the IIJ strain were crossed with females from inbred strains. All arthritic F1 mice were used to generate the F2 generation.

Adipue et al. Arthritis Research & Therapy 2011 13:R114   doi:10.1186/ar3399

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