Table 1 |
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Combined incidence of arthritis in first nine generations of IIJ straina |
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Progeny |
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Phenotype of parentsb |
Total |
Female |
Male |
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Male × Female, n (%) |
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AR × AR |
159 of 463 (34%) |
84 of 207 (41%) |
75 of 256 (29%) |
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AR × NAR |
77 of 273 (28%) |
41 of 120 (34%) |
36 of 153 (24%) |
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NAR × AR |
39 of 99 (39%) |
22 of 53 (42%) |
17 of 46 (37%) |
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NAR × NAR |
29 of 97 (30%) |
15 of 44 (34%) |
14 of 53 (26%) |
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Overall, n (%) |
304 of 932 (33%) |
162 of 424 (38%) |
142 of 508 (28%) |
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aProgeny were considered arthritic when they maintained a score of 2 (see Materials and methods for details) on the same paw for two consecutive readings. Results were combined based on phenotype of parents regardless of generation. bArthritic (AR) or nonarthritic (NAR); all were intercrosses between littermates. |
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Adipue et al. Arthritis Research & Therapy 2011 13:R114 doi:10.1186/ar3399 |
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