Table 1

Combined incidence of arthritis in first nine generations of IIJ straina

Progeny


Phenotype of parentsb

Total

Female

Male


Male × Female, n (%)

AR × AR

159 of 463 (34%)

84 of 207 (41%)

75 of 256 (29%)

AR × NAR

77 of 273 (28%)

41 of 120 (34%)

36 of 153 (24%)

NAR × AR

39 of 99 (39%)

22 of 53 (42%)

17 of 46 (37%)

NAR × NAR

29 of 97 (30%)

15 of 44 (34%)

14 of 53 (26%)

Overall, n (%)

304 of 932 (33%)

162 of 424 (38%)

142 of 508 (28%)


aProgeny were considered arthritic when they maintained a score of 2 (see Materials and methods for details) on the same paw for two consecutive readings. Results were combined based on phenotype of parents regardless of generation. bArthritic (AR) or nonarthritic (NAR); all were intercrosses between littermates.

Adipue et al. Arthritis Research & Therapy 2011 13:R114   doi:10.1186/ar3399

Open Data