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Volume 13 Issue 4

Comment

Editorial   Free

Idiopathic aortitis: an underrecognized vasculitis

Nicolò Pipitone, Carlo Salvarani Arthritis Research & Therapy 2011, 13:119 (22 July 2011)

Abstract | Full text | PDF | PubMed

Editorial   Free

Are we ready for therapeutic drug monitoring of biologic therapeutics?

Charlotte LM Krieckaert, Willem F Lems Arthritis Research & Therapy 2011, 13:120 (2 August 2011)

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Editorial   Free Highly Accessed

Green tea: a new option for the prevention or control of osteoarthritis

Santosh K Katiyar, Chander Raman Arthritis Research & Therapy 2011, 13:121 (10 August 2011)

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Editorial   Free Highly Accessed

A new weapon against an old target

Christoph Fiehn Arthritis Research & Therapy 2011, 13:122 (12 August 2011)

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Editorial   Free

Challenges in understanding Sjögren's syndrome - improved insights into the pathogenesis generate hope for innovative therapies?

Thomas Dörner Arthritis Research & Therapy 2011, 13:123 (19 August 2011)

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Editorial   Free

Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy

Xavier Chevalier, Thierry Conrozier, Pascal Richette Arthritis Research & Therapy 2011, 13:124 (26 August 2011)

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Editorial   Free Highly Accessed

More than just B-cell inhibition

Eric M Ruderman, Richard M Pope Arthritis Research & Therapy 2011, 13:125 (30 August 2011)

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Commentary   Free

Neutrophils and interferon-α-producing cells: who produces interferon in lupus?

Patrice Decker Arthritis Research & Therapy 2011, 13:118 (6 July 2011)

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Review

Review   Free Highly Accessed

Cytokine disturbances in systemic lupus erythematosus

Noam Jacob, William Stohl Arthritis Research & Therapy 2011, 13:228 (6 July 2011)

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Review   Free

Disturbance of cytokine networks in Sjögren's syndrome

Pierre Youinou, Jacques-Olivier Pers Arthritis Research & Therapy 2011, 13:227 (6 July 2011)

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Review   Free

The lung as a possible target for the immune reaction in myositis

Sonye K Danoff, Livia Casciola-Rosen Arthritis Research & Therapy 2011, 13:230 (13 July 2011)

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Review   Free Highly Accessed

MicroRNAs in systemic rheumatic diseases

Angela Ceribelli, Bing Yao, Paul R Dominguez-Gutierrez, Md A Nahid, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2011, 13:229 (13 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free

Lymphotoxin α revisited: general features and implications in rheumatoid arthritis

Flavia Calmon-Hamaty, Bernard Combe, Michael Hahne, Jacques Morel Arthritis Research & Therapy 2011, 13:232 (26 July 2011)

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Review   Free

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

Tobias Braun, Jochen Zwerina Arthritis Research & Therapy 2011, 13:235 (28 July 2011)

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Review   Free

Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors

Baohong Zhao, Lionel B Ivashkiv Arthritis Research & Therapy 2011, 13:234 (28 July 2011)

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Review   Free

Giant cell arteritis: immune and vascular aging as disease risk factors

Shalini V Mohan, Y Joyce Liao, Jonathan W Kim, Jörg J Goronzy, Cornelia M Weyand Arthritis Research & Therapy 2011, 13:231 (2 August 2011)

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Review   Free

Immunopathologic differences of Sjögren's syndrome versus sicca syndrome in HCV and HIV infection

Claudio Vitali Arthritis Research & Therapy 2011, 13:233 (19 August 2011)

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Review   Free

T-helper cells as new players in ANCA-associated vasculitides

Wayel H Abdulahad, Peter Lamprecht, Cees GM Kallenberg Arthritis Research & Therapy 2011, 13:236 (23 August 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Cardiovascular disease in systemic sclerosis - an emerging association?

Gene-Siew Ngian, Joanne Sahhar, Ian P Wicks, Sharon Van Doornum Arthritis Research & Therapy 2011, 13:237 (26 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Report

Meeting report   Free

7th meeting of the global arthritis research network

Matthias Brock, Michelle Trenkmann, Maria Filkova, Hossein Hemmatazad, Emmanuel Karouzakis, Fabienne Niederer, Kerstin Klein, Steffen Gay Arthritis Research & Therapy 2011, 13:303 (23 August 2011)

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Research

Research article   Open Access

Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain

Michael Boettger, Diana Kümmel, Andrew Harrison, Hans-Georg Schaible Arthritis Research & Therapy 2011, 13:R110 (7 July 2011)

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Research article   Open Access

Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis

Fulvia Ceccarelli, Carlo Perricone, Martina Fabris, Cristiano Alessandri, Annamaria Iagnocco, Cinzia Fabro, Elena Pontarini, Salvatore De Vita, Guido Valesini Arthritis Research & Therapy 2011, 13:R111 (8 July 2011)

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Research article   Open Access Highly Accessed

Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label

Cándido Díaz-Lagares, Roberto Pérez-Alvarez, Francisco J García-Hernández, María M Ayala-Gutiérrez, José Callejas, Agustín Martínez-Berriotxoa, Javier Rascón, Luis Caminal-Montero, Albert Selva-O'Callaghan, Joaquim Oristrell, Carmen Hidalgo, Ricardo Gómez-de-la-Torre, Luis Sáez, Jesús Canora-Lebrato, María-Teresa Camps, Norberto Ortego-Centeno, María-Jesús Castillo-Palma, Manuel Ramos-Casals, the BIOGEAS Study Group Arthritis Research & Therapy 2011, 13:R112 (11 July 2011)

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Research article   Open Access

The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1

Yu-Jung Heo, Hye-Jwa Oh, Young Jung, Mi-La Cho, Seon-Yeong Lee, Jun-Geol Yu, Mi-Kyung Park, Hae-Rim Kim, Sang-Heon Lee, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2011, 13:R113 (12 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Characterization of a novel and spontaneous mouse model of inflammatory arthritis

Iris A Adipue, Joel T Wilcox, Cody King, Carolyn AY Rice, Katherine M Shaum, Cory M Suard, Elri Brink, Stephen D Miller, Eileen J McMahon Arthritis Research & Therapy 2011, 13:R114 (12 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells

Betty Y Chang, Min Huang, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy Arthritis Research & Therapy 2011, 13:R115 (13 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients

María Teruel, Jose-Ezequiel Martin, Carlos González-Juanatey, Raquel López-Mejias, Jose A Miranda-Filloy, Ricardo Blanco, Alejandro Balsa, Dora Pascual-Salcedo, Luis Rodriguez-Rodriguez, Benjamin Fernández-Gutierrez, Ana M Ortiz, Isidoro González-Alvaro, Carmen Gómez-Vaquero, Nunzio Bottini, Javier Llorca, Miguel A González-Gay, Javier Martin Arthritis Research & Therapy 2011, 13:R116 (18 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Influence of atorvastatin on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients: a prospective, randomized, double-masked, placebo-controlled study

Wojciech Plazak, Krzysztof Gryga, Hanna Dziedzic, Lidia Tomkiewicz-Pajak, Malgorzata Konieczynska, Piotr Podolec, Jacek Musial Arthritis Research & Therapy 2011, 13:R117 (20 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay

Karl Egerer, Dirk Roggenbuck, Thomas Büttner, Barbara Lehmann, Annushka Kohn, Philipp von Landenberg, Rico Hiemann, Eugen Feist, Gerd-Rüdiger Burmester, Thomas Dörner Arthritis Research & Therapy 2011, 13:R118 (21 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Atypical clinical presentation of a subset of patients with anti-RNA polymerase III - non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining

Angela Ceribelli, Malgorzata E Krzyszczak, Yi Li, Steven J Ross, Jason YF Chan, Edward KL Chan, Rufus W Burlingame, Tyler T Webb, Michael R Bubb, Eric S Sobel, Westley H Reeves, Minoru Satoh Arthritis Research & Therapy 2011, 13:R119 (22 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration

Fackson Mwale, Koichi Masuda, Rajeswari Pichika, Laura M Epure, Tomoaki Yoshikawa, Aseem Hemmad, Peter J Roughley, John Antoniou Arthritis Research & Therapy 2011, 13:R120 (25 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

Monika Biniecka, Aisling Kennedy, Chin T Ng, Ting C Chang, Emese Balogh, Edward Fox, Douglas J Veale, Ursula Fearon, Jacintha N O'Sullivan Arthritis Research & Therapy 2011, 13:R121 (25 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Decreases in serum levels of S100A8/9 (calprotectin) correlate with improvements in total swollen joint count in patients with recent-onset rheumatoid arthritis

Lucie Andrés Cerezo, Heřman Mann, Ondřej Pecha, Lenka Pleštilová, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt Arthritis Research & Therapy 2011, 13:R122 (26 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

A targeted lipidomics approach to the study of eicosanoid release in synovial joints

Janny C de Grauw, Chris HA van de Lest, Paul van Weeren Arthritis Research & Therapy 2011, 13:R123 (27 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis

Xiaotian Chang, Yan Zhao, Xinfeng Yan, Jihong Pan, Kehua Fang, Lin Wang Arthritis Research & Therapy 2011, 13:R124 (29 July 2011)

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Research article   Open Access

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

Stanley B Cohen, Susanna Proudman, Alan J Kivitz, Francis X Burch, John P Donohue, Deborah Burstein, Yu-Nien Sun, Christopher Banfield, Michael S Vincent, Liyun Ni, Debra J Zack Arthritis Research & Therapy 2011, 13:R125 (29 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy

Der-Yuan Chen, Yi-Ming Chen, Hsin-Hua Chen, Chia-Wei Hsieh, Chi-Chen Lin, Joung-Liang Lan Arthritis Research & Therapy 2011, 13:R126 (30 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Postural control deficits in people with fibromyalgia: a pilot study

Kim D Jones, Laurie A King, Scott D Mist, Robert M Bennett, Fay B Horak Arthritis Research & Therapy 2011, 13:R127 (2 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts

Xiaodong Zhou, Wei Lin, Filemon K Tan, Shervin Assassi, Mavin J Fritzler, Xinjian Guo, Roozbeh Sharif, Tom Xia, Syeling Lai, Frank C Arnett Arthritis Research & Therapy 2011, 13:R128 (9 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts

Emily Turner-Brannen, Ka-Yee Choi, Dustin ND Lippert, John P Cortens, Robert EW Hancock, Hani El-Gabalawy, Neeloffer Mookherjee Arthritis Research & Therapy 2011, 13:R129 (11 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im Arthritis Research & Therapy 2011, 13:R130 (11 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study

Lena Innala, Bozena Möller, Lotta Ljung, Staffan Magnusson, Torgny Smedby, Anna Södergren, Marie-Louise Öhman, Solbritt Rantapää-Dahlqvist, Solveig Wållberg-Jonsson Arthritis Research & Therapy 2011, 13:R131 (15 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The occurrence of heart disease in patients with rheumatoid arthritis (RA) is potentiated by disease-related inflammation as well as traditional risk factors, which may have implications for cardioprotective strategies in RA.

Research article   Open Access

Autophagy in rat annulus fibrosus cells: evidence and possible implications

Chao Shen, Jun Yan, Lei-Sheng Jiang, Li-Yang Dai Arthritis Research & Therapy 2011, 13:R132 (16 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

Luis Rodríguez-Rodríguez, Carlos González-Juanatey, Mercedes García-Bermúdez, Tomas R Vázquez-Rodríguez, Jose A Miranda-Filloy, Benjamin Fernández-Gutiérrez, Javier Llorca, Javier Martin, Miguel A González-Gay Arthritis Research & Therapy 2011, 13:R133 (16 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Utility of a simplified ultrasound assessment to assess interstitial pulmonary fibrosis in connective tissue disorders - preliminary results

Marwin Gutierrez, Fausto Salaffi, Marina Carotti, Marika Tardella, Carlos Pineda, Chiara Bertolazzi, Elisabetta Bichisecchi, Emilio Filippucci, Walter Grassi Arthritis Research & Therapy 2011, 13:R134 (18 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Subgroups of older adults with osteoarthritis based upon differing comorbid symptom presentations and potential underlying pain mechanisms

Susan L Murphy, Angela K Lyden, Kristine Phillips, Daniel J Clauw, David A Williams Arthritis Research & Therapy 2011, 13:R135 (24 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts

Heidi Wähämaa, Hanna Schierbeck, Hulda S Hreggvidsdottir, Karin Palmblad, Anne-Charlotte Aveberger, Ulf Andersson, Helena Harris Arthritis Research & Therapy 2011, 13:R136 (26 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism

Kyle D Allen, Mohammed F Shamji, Brian A Mata, Mostafa A Gabr, S Michael Sinclair, Daniel O Schmitt, William J Richardson, Lori A Setton Arthritis Research & Therapy 2011, 13:R137 (26 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

CD23+/CD21hi B-cell translocation and ipsilateral lymph node collapse is associated with asymmetric arthritic flare in TNF-Tg mice

Jie Li, Quan Zhou, Ronald W Wood, Igor Kuzin, Andrea Bottaro, Christopher T Ritchlin, Lianping Xing, Edward M Schwarz Arthritis Research & Therapy 2011, 13:R138 (31 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

The association between systemic glucocorticoid therapy and the risk of infection in patients with rheumatoid arthritis: systematic review and meta-analyses

William G Dixon, Samy Suissa, Marie Hudson Arthritis Research & Therapy 2011, 13:R139 (31 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear factor-κB ligand

Helen E Gruber, Jane A Ingram, Gretchen L Hoelscher, Natalia Zinchenko, H James Norton, Edward N Hanley Arthritis Research & Therapy 2011, 13:R140 (31 August 2011)

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Correspondence

Letter   Free

Response to 'Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study'

Kazuki Yoshida, Kazuo Matsui, Hiroto Nakano, Hideto Oshikawa, Masako Utsunomiya, Tatsuo Kobayashi, Makiko Kimura, Gautam A Deshpande, Mitsumasa Kishimoto Arthritis Research & Therapy 2011, 13:405 (18 August 2011)

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