Figure 8.

Model for interactions possibly occurring in cultured articular chondrocytes during inflammation and resolution of inflammation. 15ΔPGJ2, 15-deoxy-Δ^12,14-prostaglandin J_2,; COX-2, cyclooxygenase-2; DGDG, digalactosyldiacylglycerol; IL-1, interleukin-1; IL-6, interleukin-6; IL-8, interleukin-8; MGDG, monogalactosyldiacylglycerol; mPGES, microsomal PGE synthase; NF-kB, nuclear factor-kappaB; P1, cell passage number1; p38, p38 mitogen activated protein kinase; PGE₂, prostaglandin E₂; TNFα, tumor necrosis factor alpha.