Serum HMGB1 after IgG depletion. HMGB1 levels are decreased in serum depleted of IgG from an SLE patient. The first lane represents the standard control consisting of human keratinocyte HaCaT cells; the second lane represents the HMGB1 amount in the serum of a SLE patient before IgG depletion and in the third lane the HMGB1 amount after IgG depletion in the serum of same patient is shown.
Abdulahad et al. Arthritis Research & Therapy 2011 13:R71 doi:10.1186/ar3332