Table 2 |
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|
Histomorphometric results for each mice group |
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|
Normal control group |
Sham-OVX group |
OVX group |
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|
|
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|
OVX + Vehicle |
OVX+E |
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|
PE (-) |
PE (+) |
PE (-) |
PE (+) |
PE (-) |
PE (+) |
PE (-) |
PE (+) |
|
|
SSA (mm2) |
0.036 ± 0.008 (0.008 to .076) |
0.10 ± 0.04 (0.05 to 0.33) |
0.034 ± 0.007 (0.008 to 0.07) |
0.093 ± 0.03 (0.05 to 0.34) |
0.026 ± 0.01 (0.006 to 0.1) |
0.09 ± 0.04 (0.01 to 0.35) |
0.038 ± 0.01 (0.01 to 0.11) |
0.20 ± 0.05 (0.07 to 0.46) |
|
BT/TT |
60 ± 4.7% (42% to 80%) |
48 ± 5.3% (23% to 73%) |
62 ± 4.6% (49% to 80%) |
45 ± 4% (23% to 56%) |
55 ± 5.2% (35% to 73%) |
49 ± 4.9% (26% to 65%) |
54 ± 5.5% (31% to 73%) |
37 ± 5.1% (17% to 55%) |
|
Δ(BT/TT) |
-12 ± 5.3% (-37% to 12%) |
-16 ± 4.5% (-39% to 5%) |
-6.7 ± 4.9% (-30% to 9%) |
-17 ± 5% (-37% to 1.2%) |
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|
Oc Nb |
0.31 ± 0.3 (0 to 2) |
2.2 ± 0.7 (0 to 5) |
0.42 ± 0.3 (0 to 2) |
2.5 ± 0.7 (0 to 5) |
0.65 ± 0.4 (0 to 3) |
0.7 ± 0.5 (0 to 4) |
0.27 ± 0.2 (0 to 1) |
2.1 ± 0.8 (0 to 6) |
|
|
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|
Values are expressed as mean ± standard error of the mean (extremes). BT, bone thickness; E, oestrogen; Oc Nb, osteoclast number; OVX, ovariectomy; PE, polyethylene; PE(-), sham-implanted; PE(+), PE-implanted; SSA, sagittal suture area; TT, tissue thickness. |
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|
Nich et al. Arthritis Research & Therapy 2011 13:R100 doi:10.1186/ar3381 |
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