Effect of polyethylene particles on trabecular thickness (Tb.Th), as assessed by longitudinal 3D micro-CT. Trabecular thickness was not altered by the presence of particles in ovariectomized (OVX) mice, as opposed to the other mice groups. Trabecular thickness was quantified using CTAn software. The data are presented as means ± standard error of the mean (a indicates P < 0.005; b indicates P < 0.05, compared to internal control, using Student's t-test).
Nich et al. Arthritis Research & Therapy 2011 13:R100 doi:10.1186/ar3381