Figure 4.

Algorithm for the management of patients with a rheumatic condition requiring anti-rheumatic (immunosuppressive) treatment in the context of a current or past malignancy. A detailed description of the algorithm is presented in the 'Suggested management' section. *The term 'remission' implies that the disease has been either eliminated or substantially reduced; the RECIST (Response Evaluation Criteria In Solid Tumors) criteria may be used for the evaluation of remission [65]. **Risk-of-relapse categories are based on Penn [53]: low risk (0% to 10%) for testicular cancer, uterine cervical cancer, incidental renal cancer, lymphoma, and thyroid cancer; intermediate risk (11% to 25%) for corpus uteri, Wilms' tumor, colon cancer, prostate cancer, and breast cancer; and high risk (>25%) for bladder cancer, renal cancer, sarcoma, skin cancer (melanoma and non-melanomatous), and multiple myeloma.