Table 3

Renal manifestations of systemic diseases commonly seen by rheumatologists

Disease

Renal manifestation


Rheumatoid arthritis

Mesangial GN, renal amyloidosis, membranous GN

Spondylarthropathy/psoriasis arthritis

Renal amyloidosis, IgA nephropathy

Systemic lupus erythematosus

Lupus nephritis: proliferative immune complex GN, membranous GN

Sjögren's syndrome

Interstitial nephritis with renal tubular acidosis (type 1)

ANCA vasculitis

Crescentic (pauci-immune) GN, interstitial nephritis

Giant cell arteritis

Renal artery stenosis

Immune complex disease

Immune complex GN

Diffuse cutaneous systemic scleroderma

Scleroderma renal crisis, crescentic GN (with myeloperoxidase ANCA), interstitial nephritis, chronic (ischemic) kidney disease

Sarcoidosis

Nephrocalcinosis, nephrolithiasis, granulomatous interstitial nephritis

Malignancy

Nephrotic syndrome (membranous GN, minimal change disease, focal glomerulosclerosis)

Diabetes

Chronic kidney disease: diabetic nephropathy

Hypertension

Chronic kidney disease: hypertensive nephropathy


ANCA, anti-neutrophil cytoplasmic antibody; GN, glomerulonephritis.

Anders and Vielhauer Arthritis Research & Therapy 2011 13:222   doi:10.1186/ar3256