Table 5

Changes in transcription factors

rhOP-1 vs Cntr

rhOP-1AS vs Cntr

fold change

fold change

Accession no.


Transcription factor 8 (represses IL-2 expression)

3.28↓

2.97↓

[GenBank:NM_030751]

NF-κB2

2.77↓

[GenBank:NM_002502]

STAT1

2.42↓

[GenBank:NM_007315]

Transcription factor AP-2α

2.07↓

1.52↓

[GenBank:NM_003220]

Suppression of tumorigenicity

2.04↓

2.20↓

[GenBank:NM_013437]

Runx1

1.89↓

1.64↓

[GenBank:NM_001754]

NFκBIα

1.86↓

1.58↑

[GenBank:NM_020529]

NFYβ

1.68↓

1.75↓

[GenBank:NM_006166]

Activating transcription factor 7

1.66↓

[GenBank:NM_006856]

MADS box transcription enhancer factor 2-d

1.65↓

[GenBank:NM_005920]

Upstream transcription factor 2, c-fos interacting

1.58↓

[GenBank:NM_003367]

Transcription factor (p38 interacting protein)

1.57↓

[GenBank:NM_017569]

MADS box transcription enhancer factor 2-C

1.60↑

1.94↓

[GenBank:NM_002397]

Protein inhibitor of activated STAT3

1.84↓

[GenBank:NM_006099]

Ubiquitin-like 1 (sentrin)

1.60↓

[GenBank:NM_003352]

STAT6

1.53↓

[GenBank:NM_003153]


Chubinskaya et al. Arthritis Research & Therapy 2011 13:R55   doi:10.1186/ar3300

Open Data