Serum antibody levels measured by ELISA in RA patients and community-derived control subjects. ANA levels in RA patients from DRADR (L panel) were significantly higher in females than in males. By contrast, CCP antibodies measured in individuals from the Dallas Heart Study (middle panel) or in DRADR RA patients (right panel) did not show significant male-female differences.
Li et al. Arthritis Research & Therapy 2011 13:R38 doi:10.1186/ar3271