Table 3

Adjusted odds ratios and 95% confidence intervals for associations between knee outcomes, continuous ln Pb and covariates (joint-based analysis)a

Knee rOA

Knee sxOA


Variable of interest (reference category)

aORb

95% CI

aORb

95% CI


ln Pb (per 1-U change)

1.20

1.01 to 1.44

1.16

0.93 to 1.45

Age (per year)

1.08

1.07 to 1.09

1.05

1.03 to 1.06

BMI (per kg/m2)

1.12

1.10 to 1.14

1.12

1.10 to 1.14

Sex (men)

0.96

0.77 to 1.21

1.24

0.94 to 1.63

Race (Caucasian)

1.08

0.85 to 1.36

0.84

0.64 to 1.11

Smoking (No)

0.60

0.43 to 0.85

0.59

0.38 to 0.91

Drinking (No)

0.75

0.57 to 1.00

0.72

0.50 to 1.03


aReference category is no rOA for rOA outcomes and rOA without symptoms for sxOA outcomes; aOR, adjusted odds ratio; CI, confidence interval; ln Pb, natural log-transformed lead; rOA, radiographic osteoarthritis; sxOA, symptomatic osteoarthritis; BMI, body mass index; badjusted for age, sex, race and ethnicity, BMI, current smoking and current drinking.

Nelson et al. Arthritis Research & Therapy 2011 13:R37   doi:10.1186/ar3270

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