Table 1

Peripheral and central quantitative sensory testing findings in fibromyalgia, osteoarthritis and rheumatoid arthritis

Peripheral findings

Central findings



Low pain thresholds at affected sites

Low pain thresholds in a widespread distribution

Loss of descending analgesia (conditioned pain modulation)

Temporal summation

Expanded areas of hyperalgesia


Fibromyalgia

X

X

X

X

X

Osteoarthritis

X

X

X

X

X

Rheumatoid arthritis

X

X

X

X


Lee et al. Arthritis Research & Therapy 2011 13:211   doi:10.1186/ar3306