Figure 2.

Canonical and non-canonical (Abl) Notch signaling pathways. A, co-activator; CSL, CBF, Su(H), Lag3; DSL, Delta, Serrate, Lag2; R, co-repressor; S1, S2, S3 and S4, Notch cleavage sites in the canonical signaling pathway; TACE, tumor necrosis factor alpha converting enzyme.