Figure 3.

Schematic showing the CD3ΞΆ gene. Genomic DNA with eight exons (top), the mRNA with a full-length 906-bp 3' UTR (WT; middle) and the 344-bp alternatively spliced (AS) 3' UTR variant (bottom). SLE T cells express increased amounts of the unstable AS splice variant relative to the stable WT isoform.

Moulton and Tsokos Arthritis Research & Therapy 2011 13:207   doi:10.1186/ar3251
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