Can ultrasonography make identification of asymptomatic hyperuricemic individuals at risk for developing gouty arthritis more crystal clear?
Division of Rheumatology, Department of Medicine, UMDNJ - Robert Wood Johnson Medical School, MEB 468, One Robert Wood Johnson Pl., P.O. Box 19, New Brunswick, NJ 08903-0019, USA
Arthritis Research & Therapy 2011, 13:107 doi:10.1186/ar3290Published: 19 April 2011
Hyperuricemia is the most important risk factor for gouty arthritis. The quandary is how to predict which patient with asymptomatic hyperuricemia will develop gouty arthritis. Can ultrasonography help identify hyperuricemic individuals at risk for developing gouty arthritis? In the previous issue of Arthritis Research & Therapy, Pineda and colleagues found ultrasonography changes suggestive of gouty arthritis in 25% of hyperuricemic individuals. These were found exclusively in hyperuricemic individuals but not in normouricemic patients. Ultrasonography may serve as a noninvasive means to diagnose gouty arthritis in hyperuricemic individuals who have yet to develop symptomatic gouty arthritis.