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Relationships between biomarkers of cartilage, bone, synovial metabolism and knee pain provide insights into the origins of pain in early knee osteoarthritis

Muneaki Ishijima*, Taiji Watari, Kiyohito Naito, Haruka Kaneko, Ippei Futami, Kaori Yoshimura-Ishida, Akihito Tomonaga, Hideyo Yamaguchi, Tetsuro Yamamoto, Isao Nagaoka, Hisashi Kurosawa, Robin A Poole and Kazuo Kaneko

Arthritis Research & Therapy 2011, 13:R22  doi:10.1186/ar3246

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