Table 1

Characteristics and serum FSTL1 levels of the subjects investigateda

Characteristics

RA

ReA

PsA

AS

CD

UC

SLE

pSS

sSS

SSc

PM/DM

HC


Total number of subjects

207

22

34

33

20

22

40

16

28

22

43

69

Ageb, years

54

23.5

46.5

44

33

35

37

50

53

53.5

41

38

25th percentile

43.5

13.8

33

29.5

25.5

29.3

31.3

48

39.3

43.5

26

27

75th percentile

63

33.5

54

51

43

45.8

52.3

63

63

58

58

41

Number of female/male subjects

159/48

8/14

15/19

9/24

6/14

9/13

34/6

14/2

24/4

17/5

31/12

37/32

Disease durationb, years

3

20 days

5

2

3

4

4

2

3

2

1

-

25th percentile

0.5

13 days

3

1

1

2

1

1

1

1

0.3

-

75th percentile

10

75 days

7

4

6

7

6

4

8

5

2

-

Serum FSTL1 levels, μg/l

Geometric mean

74.28

3.74

7.57

6.19

6.39

13.61

14.60

29.94

73.88

16.48

13.79

6.49

Lower 95% CI

60.89

2.73

4.99

5.03

5.35

9.71

10.49

15.76

45.79

7.81

9.97

5.89

Upper 95% CI

90.60

5.12

11.48

7.62

7.63

19.06

20.30

56.88

119.20

34.76

19.06

7.15

RSD (%)

129.17

104.58

134.90

63.33

39.06

112.35

115.27

148.22

117.81

133.00

186.28

36.71

Median

71.27

3.71

4.52

5.21

6.05

10.78

12.92

34.81

82.48

25.01

10.74

6.60

25th percentile

25.51

2.49

3.47

3.67

4.92

7.48

6.84

10.51

23.48

3.38

6.76

5.28

75th percentile

236.70

5.46

29.59

9.37

8.55

28.24

34.12

47.37

169.70

62.68

29.60

8.19

Above normal, %c

87.43

9.09

26.47

18.18

5

36.36

52.5

68.75

96.43

54.55

48.84

4.3

P versus HC

<0.001

<0.001

0.100

0.375

0.627

<0.001

<0.001

<0.001

<0.001

<0.001

0.018

-

P versus RA

-

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

0.013

0.937

<0.001

<0.001

<0.001


aFSTL1, follistatin-like protein 1; 95% CI, 95% confidence interval; -, not determined; RSD, relative standard deviation; HC, healthy individuals; RA, rheumatoid arthritis; ReA, reactive arthritis; PsA, psoriatic arthritis; AS, ankylosing spondylitis; CD, Crohn's disease; UC, ulcerative colitis; SLE, systemic lupus erythematosus; pSS, primary Sjögren's syndrome; sSS, secondary Sjögren's syndrome; SSc, systemic sclerosis; PM/DM, polymyositis/dermatomyositis; bmedian; cnormal range denoted as mean + 2 SD was 12 μg/l.

Li et al. Arthritis Research & Therapy 2011 13:R17   doi:10.1186/ar3241

Open Data