Research article
A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis
Division of Rheumatology and Rheumatic Diseases Research Core Center, Department of Internal Medicine, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Arthritis Research & Therapy 2011, 13:R15 doi:10.1186/ar3239
Published: 4 February 2011Additional files
Additional file 1:
Table S1, Supplemental Figures S1 and S2. Table S1. Baseline characteristics of study patients. Figure S1. Regulation of interleukin-17 production in vitro. Figure S2. Inhibition of interleukin (IL)-17 production by IL-4: effect of IL-4R genotype in rheumatoid arthritis patients.
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