Table 3 |
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|
Regression analysis of mannose-binding lectin genotype groups and pregnancy outcome measures based on dichotomous variablesa |
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|
MBL genotype groups A, B and C (three strata) |
MBL genotype group A vs. B plus C (dichotomous) |
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|
|
|
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|
Variable stratified |
OR |
95% CI |
n |
OR |
95% CI |
n |
|
|
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|
Miscarriage |
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|
No correction |
1.13 |
0.64 to 1.99 |
21/205 |
1.31 |
0.53 to 3.23 |
21/205 |
|
Correction for all confounders |
0.99 |
0.53 to 1.83 |
20/178 |
1.12 |
0.43 to 2.87 |
20/178 |
|
Hypertension |
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|
No correction |
0.93 |
0,53 to 1.66 |
23/174 |
0.72 |
0.30 to 1.78 |
23/174 |
|
Correction for all confounders |
0.76 |
0.36 to 1.61 |
16/127 |
0.58 |
0.18 to 1.83 |
16/127 |
|
Gestational age (<37 wk) |
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|
No correction |
1.30 |
0.68 to 2.58 |
14/157 |
1.20 |
0.40 to 3.60 |
14/157 |
|
Correction for all confounders |
2.12 |
0.80 to 5.60 |
13/127 |
2.38 |
0.47 to 12.1 |
13/127 |
|
Low birth weight (<2,500 g) |
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|
No correction |
0.93 |
0.40 to 2.28 |
10/158 |
0.76 |
0.21 to 2.82 |
10/158 |
|
Correction for all confounders |
0.92 |
0.30 to 2.90 |
9/127 |
0.87 |
0.14 to 5.38 |
9/127 |
|
|
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|
aDichotomous variable outcome measures include miscarriage, hypertension, gestational age and low birth weight in patients with rheumatoid arthritis. MBL, mannose-binding lectin; A, B and C, MBL production genotype groups A (high), B (intermediate) and C (low); OR, odds ratio; 95% CI, 95% confidence interval. |
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|
van de Geijn et al. Arthritis Research & Therapy 2011 13:R10 doi:10.1186/ar3231 |
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