Research article
High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes
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* Corresponding author: Maria José Alcaraz maria.j.alcaraz@uv.es
1 Department of Pharmacology, University of Valencia, Av.Vicent Andrés Estellés s/n, Burjasot, 46100 Valencia, Spain
2 Department of Chemistry, Biochemistry and Molecular Biology, Cardenal Herrera-CEU University, Av. Seminario s/n, Moncada, 46113 Valencia, Spain
3 Department of Surgery, School of Medicine, University of Valencia, Av. Blasco Ibáñez 15, Valencia, 46010 Valencia, Spain
4 Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, 1560 Rue Sherbrooke East, Montreal, Quebec H2L 4M1, Canada
Arthritis Research & Therapy 2010, 12:R165 doi:10.1186/ar3124
Published: 27 August 2010Additional files
Additional file 1:
Supplementary figure S1. Time course of high mobility group box 1 (HMGB1) and IL-1β effects on Akt and mitogen-activated protein kinase (MAPK) phosphorylation.
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