Table 2

Comparisons of CD64 expression (mean fluorescence intensity) with disease manifestations and medication use

Yes

No

P value


Disease manifestations

Skin

495.2 ± 15.9

455.5 ± 14.1

0.0423

Photosensitivity

502.3 ± 16.0

446.9 ± 14.4

0.0103

Joint

479.3 ± 13.2

456.4 ± 17.2

0.3481

Renal

499.2 ± 14.4

448.7 ± 15.4

0.0172

CNS

463.3 ± 24.8

475.1 ± 11.6

0.7092

Serositis

488.9 ± 18.9

462.6 ± 12.5

0.2294

Pleurisy

499.0 ± 23.3

463.1 ± 11.9

0.1328

Pericarditis

558.8 ± 26.8

450.7 ± 10.9

< 0.0001

Hematologic abnormalities

495.0 ± 15.3

446.2 ± 14.2

0.0226

Anti-dsDNA

507.0 ± 13.8

439.5 ± 17.9

0.0030

Anti-Sm

489.9 ± 12.0

399.7 ± 23.7

0.0022

Anti-phospholipid

476.0 ± 15.7

476.2 ± 15.4

0.9946

Medications

Corticosteroids

528.5 ± 20.4

512.9 ± 24.9

0.6409

Antimalarials

510.4 ± 18.1

556.0 ± 31.9

0.1967

Cytotoxic agents

503.9 ± 16.7

557.9 ± 22.6

0.1080

Statins

517.1 ± 37.9

483.9 ± 16.7

0.4460


Differences between groups were analyzed by using Student's t test. A P value < 0.05 is considered statistically significant. Hematologic abnormalities include autoimmune hemolytic anemia, WBC <4,000/μL, absolute lymphocyte count <1,500/μL, and platelets <100,000/μL.

Li et al. Arthritis Research & Therapy 2010 12:R90   doi:10.1186/ar3017

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